TOPlistModified GRF 1-29 (CJC-1295 WITHOUT DAC) 5mg Particle | Steroids4U.eu
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Mod GRF 1-29 (CJC-1295 WITHOUT DAC) - 5mg Particle

1 vial/5mg

Product name: Modified GRF 1-29 - 5mg

Substance: Peptide

Manufacturer: Particle Peptides

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Read The Spec Sheet Below Before You Buy CJC-1295 No-Dac:

Unit Size

5 mg/vial

Unit Quantity

1 Vial

CAS NO.

863288-34-0

Synonyms

CJC-1295 without DAC, CJC 1295 w/o DAC

Molecular Formula

C152H252N44O42

Molecular Weight

3367.97

Sequence

H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2

Appearance

White Powder

Purity

98.59 %

Identity (ESI-MS)

3367.97±3.0

Source

Chemical Synthesis

Storage

Lyophilized CJC-1295 W/O DAC is stable at room temperature for 90 days, however it should be stored in a freezer below -8C for any extended period of time. After reconstituting CJC-1295 W/O DAC should be refrigerated at temperatures not to exceed 36 F.

CJC-1295 No-DAC – 5 MG (MOD GRF 1-29)

Modified Growth Releasing Factor aminos 1-29, usually referred to as Modified GRF (1-29) or “ModGRF(1-29),” also known as CJC-1295 without DAC, is a synthetic analog of the endogenous peptide signaling hormone Growth Hormone Releasing Hormone (GHRH). Endogenously produced GHRH has 44 amino acids in its chain structure. A truncated synthetic form of GHRH called Sermorelin or GRF 1-29 has 29 amino acids; Modified GRF (1-29) is further changed in that it has four substituted aminos in its chain that serve the purposes of preventing degradation and oxidation in manufacture and transport as well as in vivo, while also increasing binding affinity to the GHRH receptors.


Modified GRF (1-29) is not CJC-1293 nor should it be referred to as such. Modified GRF (1-29) is identical to the portion of CJC-1295 DAC that is not bound to MPA, minus the lysine. The presence of lysine in a literal “CJC without DAC” in the absence of MPA would have the opposite effect of DAC: it would drastically reduce the active life of the peptide to that of Sermorelin. Modified GRF (1-29) is the same as CJC-1295 without DAC.

 

Tetrasubstitued GRF (1-29)

Modified GRF (1-29) is a synthetic modification of growth hormone releasing factor (GRF) with D-Ala, Gln, Ala, and Leu substitutions at positions 2, 8, 15, and 27 respectively. These substitutions create a much more stable peptide with the substitution at position 2 to prevent DPP-IV cleavage, position 8 to reduce asparagine rearrangement or amide hydrolysis to aspartic acid, position 15 to enhance bioactivity, and position 27 to prevent methionine oxidation.

 

CJC-1295 + DAC vs. CJC-1295 without DAC

CJC-1295 + DAC and CJC-1295 (also known as Modified GRF 1-29) are both Growth Hormone Releasing Hormones (GHRH). Their action in the human body is identical but the difference between the two peptides are the span of the half-life. Modified GRF 1-29 and Sermorelin have a very short acting half-life of about 30 minutes, while CJC-1295 + DAC has a half-life that can last up to approximately 8 days. Many a scientist have reported that the short half-life of Sermorelin and Modified GRF 1-29 is considered to be much more natural as they produce a short pulse of Human Growth Hormone.

 

Purely for Scientific Research

Despite the fact that there has been plenty of research on Modified GRF 1-29 in relation to how it functions and the benefits that can be derived from such functionality, it should be emphasized that the peptide is still just intended for scientific study at this point in time.  Because of this, any findings or observations relating to Modified GRF 1-29 overall functionality, mechanics, benefits,  should exclusively be the product of study performed in a strictly contained environment.

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